What is NucleoFILL?

NucleoFILL is a preparation for deep skin renewal and bio-restructuring. This innovative treatment works on three levels: lifting, antioxidation and hydration.

This scientifically proven method of skin bio stimulation contains polynucleotides that stimulate the skin to rebuild in a three-way mechanism.

The first action is the receptors on fibroblasts in the skin, which transform into myofibroblasts. The process of the production of type I collagen and elastin is stimulated, which causes the skin to thicken and lift. The second mechanism is the “scavenging” of free radicals and antioxidant activity. The third is by way of Polynucleotides which bind water and ensure long-term iso-osmotic hydration of the extracellular matrix. As a result, the skin becomes moisturized and supple.

Nucleofill is a relatively new bio-stimulator for skin rejuvenation and protection. As an anti-ageing treatment, it is designed to help cells retain water, improve skin elasticity and tightness, and aid in the prevention of wrinkles. Unlike Profhilo, Nucleofill offers various products for specific concerns and, as well as skin regeneration, there are also options for the neck, eyes, and even the scalp to stimulate hair growth.

What are the key differences between Profhilo and NucleoFILL

The way in which Nucleofill differs from familiar injectables such as Profhilo is that it’s a bio-stimulant gel, rather than hyaluronic acid. Yet it still does the all-important job of stimulating fibroblasts – the major cells responsible for the production of collagen. Nucleofill directly stimulates specific receptors on the fibroblast cells and produces the healthy collagen that we have in our youth. While both treatments are highly effective, they each have their own ideal candidate. Nucleofill is fantastic for the more mature age group as it regenerates sagging and dehydrated skin and thickens the tissues. It also lasts longer than Profhilo – up to a year after two treatments.

NucleoFILL FAQ's

Which treatment is best for me?

Nucleofill is used for patients who are concerned with fine lines and wrinkles and loss of elasticity on the face or neck. Nucleofill treats various indications, including under-eye crepiness, wrinkles, and hollows. It can be combined with other treatments or used in isolation.

Indications

  • hypoxic skin
  • skin exposed to oxidative stress
  • dehydrated skin
  • stretch marks and scars

In order to obtain the best results, NucleoFILL is performed in a series of 3-4 treatments every 2-4 weeks.

NucleoFILL comes in three forms:

  • NucleoFILL Soft (also known as nucleofill eyes)
  • NucleoFILL Medium – contains 1.5ml of 2% polynucleotide
  • NucleoFILL Strong – contains 1.5ml of 2.5% polynucleotide

Procedure time

45 minutes

Price

NucleoFILL Medium-application of one ampoule £ 195 Each subsequent treatment in the series 10% discount – £ 175

NucleoFILL Strong-application of one ampoule £ 225 Each subsequent treatment in the series 10% discount- £ 200

NucleoFILL Medium and NucleoFILL Strong combined therapy – application of one ampoule of NucleoFILL Medium plus application of one ampule of NucleoFILL Strong £ 310 (Each subsequent treatment in the series 10% discount – £ 280)

Some patients may require combination therapy, i.e. the Strong dose is applied to the middle of the face and the Medium dose is applied to the lower face and chin or neck. Such therapy allows for better effects and simultaneous treatment of the face and neck.

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